Trial intelligence / Profile preview

Phase 3 study of AOC 1020 in facioscapulohumeral muscular dystrophy

NL-OMON60378Phase 3Recruiting

Sponsor
Avidity Biosciences
Start
Apr 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
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Overview

Phase 3 trial of delpacibart braxlosiran in facioscapulohumeral muscular dystrophy (FSHD), sponsored by Avidity Biosciences. Primary endpoint: Change from baseline to Week 78 in 10-meter walk/run test velocity. Started Apr 2026; status: recruiting.

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Drugs

delpacibart braxlosiran
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Conditions

facioscapulohumeral muscular dystrophy (FSHD)

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