Trial intelligence / Profile preview

DREAMM-7: belantamab mafodotin + bortezomib + dexamethasone versus daratumumab + bortezomib + dexamethasone in relapsed/refractory multiple myeloma

NL-OMON60381Phase 3Active, not recruiting

Sponsor
GSK
Start
Nov 2020
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Reversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in multiple myeloma (MM) comparing Belantamab mafodotin + bortezomib + dexamethasone with Daratumumab + bortezomib + dexamethasone (2 arms). Primary endpoint: Progression-free survival. Started Nov 2020; status: active, not recruiting.

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Drugs

belantamab mafodotindaratumumabbortezomibdexamethasone
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Conditions

multiple myeloma (MM)

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