Trial intelligence / Profile preview

LTX-002 intrathecal safety and PK study in adults with amyotrophic lateral sclerosis

NL-OMON60383Phase 2Recruiting

Sponsor
Leal Therapeutics
Start
May 2026
Modality
Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
Countries
1
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Overview

Phase 2, randomised, double-blind trial in amyotrophic lateral sclerosis (ALS) comparing LTX-002 with Placebo (2 arms). Primary endpoints: Incidence and severity of adverse events, Clinical laboratory tests and 3 more. Started May 2026; status: recruiting.

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Drugs

LTX-002
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Conditions

amyotrophic lateral sclerosis (ALS)

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