Trial intelligence / Profile preview

Phase 3 trial of epcoritamab versus investigator's choice chemotherapy in relapsed or refractory diffuse large B-cell lymphoma

NL-OMON60392Phase 3Active, not recruiting

Sponsor
Genmab
Start
Jul 2021
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Countries
1
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Overview

Phase 3, randomised, open-label trial in diffuse large B-cell lymphoma (DLBCL), large-cell lymphoma, follicular lymphoma (FL) and 2 more comparing Epcoritamab with Investigator's choice standard of care (2 arms). Primary endpoints: Overall survival and Progression-free survival by independent review. Started Jul 2021; status: active, not recruiting.

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Drugs

epcoritamab
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Conditions

diffuse large B-cell lymphoma (DLBCL)large-cell lymphomafollicular lymphoma (FL)T-cell/histiocyte-rich large B-cell lymphoma (THRLBCL)mature B-cell lymphoma

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