Trial intelligence / Profile preview

DIAN-TU trial of anti-amyloid/anti-tau disease-modifying treatment in dominantly inherited Alzheimer's disease

NL-OMON60430Phase 3Active, not recruiting

Sponsor
Washington University School of Medicine
Start
May 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals
Countries
1
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Overview

Phase 3, randomised, double-blind trial of etalanetug, lecanemab and carbon-11 Pittsburgh compound B in Alzheimer's disease (AD) (4 arms), sponsored by Washington University School of Medicine. Primary endpoints: E2814 symptomatic cohort endpoint and E2814 asymptomatic cohort endpoint. Started May 2023; status: active, not recruiting.

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Drugs

etalanetuglecanemabcarbon-11 Pittsburgh compound B
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Conditions

Alzheimer's disease (AD)

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