Trial intelligence / Profile preview

IZABRIGHT-Lung01 in EGFR-mutated NSCLC after failure of third-generation EGFR TKI therapy

NL-OMON60521Phase 3Not yet recruiting

Sponsor
Bristol Myers Squibb
Start
Jan 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
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01

Overview

Phase 3, randomised trial of izalontamab brengitecan in non-small cell lung cancer (NSCLC), sponsored by Bristol Myers Squibb. Primary endpoints: Recommended phase 3 dose and Progression-free survival. Planned start Jan 2026; status: not yet recruiting.

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Drugs

izalontamab brengitecan
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Conditions

non-small cell lung cancer (NSCLC)

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