Trial intelligence / Profile preview

PACMAN-Hu19 trial of locally produced CD19-targeted CAR T-cell therapy

NL-OMON60532Phase 2Not yet recruiting

Sponsor
Princess Máxima Center for Pediatric Oncology
Start
Jan 2026
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies, Gene Therapies
Countries
1
01

Overview

Phase 2, open-label trial of MB-HUCART19.1 in acute lymphoblastic leukemia (ALL) and mature B-cell lymphoma (2 cohorts), sponsored by Princess Máxima Center for Pediatric Oncology. Primary endpoint: Dose-limiting toxicity incidence and RP2D determination. Planned start Jan 2026; status: not yet recruiting.

02

Drugs

MB-HUCART19.1
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Conditions

acute lymphoblastic leukemia (ALL)mature B-cell lymphoma

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