Trial intelligence / Profile preview

BGB-16673 versus pirtobrutinib in relapsed/refractory CLL or SLL

NL-OMON60593Phase 3Recruiting

Sponsor
BeOne Medicines
Start
Feb 2026
Modality
Small Molecules, PROTACs (E3 ligase recruitment) → Targeted Protein Degraders (TPDs) → Small Molecules, Bivalent/Multivalent Binders → Multivalent & Scaffold-Based Small Molecules → Small Molecules
Countries
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Overview

Phase 3, randomised, open-label trial in chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) comparing BGB-16673 with Pirtobrutinib (2 arms). Primary endpoint: Progression-free survival. Started Feb 2026; status: recruiting.

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Drugs

catadegbrutinibpirtobrutinib
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Conditions

chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL)

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