Trial intelligence / Profile preview

PONTIAC: trastuzumab deruxtecan versus CDK4/6 inhibitor plus endocrine therapy in first-line HR-positive HER2-low/ultralow non-luminal advanced breast cancer

NL-OMON60596Phase 2Recruiting

Sponsor
MEDSIR
Start
Jun 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
01

Overview

A Phase 2 trial of trastuzumab deruxtecan in breast cancer, sponsored by MEDSIR. Started Jun 2026; status: recruiting.

02

Drugs

trastuzumab deruxtecan
03

Conditions

breast cancer

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