Trial intelligence / Profile preview

Pegcetacoplan for post-transplant recurrent C3G or IC-MPGN

NL-OMON60608Phase 2Completed

Sponsor
Apellis Pharmaceuticals
Start
Dec 2021
Modality
PEGylated Peptides → Modified Peptides → Peptides, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 2, randomised, open-label trial of pegcetacoplan in Complement 3 glomerulopathy (C3G) and Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN) (2 arms), sponsored by Apellis Pharmaceuticals. Primary endpoint: Proportion of subjects with reduction in C3c staining on renal biopsy after 12 weeks. Started Dec 2021; status: completed.

02

Drugs

pegcetacoplan
03

Conditions

Complement 3 glomerulopathy (C3G)Immune Complex Membranoproliferative Glomerulonephritis (IC-MPGN)

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