Trial intelligence / Profile preview

Transplant BRaVE NHL

NL-OMON60717Phase 2Active, not recruiting

Sponsor
HOVON
Start
Mar 2018
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of brentuximab vedotin in diffuse large B-cell lymphoma (DLBCL), primary mediastinal large B-cell lymphoma (PMBCL) and non-Hodgkin lymphoma (NHL), sponsored by HOVON. Primary endpoints: Serious toxicity rate during cycles 1-2, Metabolic complete response rate after cycle 3 and 1 more. Started Mar 2018; status: active, not recruiting.

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Drugs

brentuximab vedotin
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Conditions

diffuse large B-cell lymphoma (DLBCL)primary mediastinal large B-cell lymphoma (PMBCL)non-Hodgkin lymphoma (NHL)

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