Trial intelligence / Profile preview

RASTRIC triplet therapy study in RAS-mutant metastatic colorectal cancer

NL-OMON60729Phase 2Completed

Sponsor
University Medical Center Utrecht
Start
Jul 2020
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of binimetinib, lapatinib and vinorelbine in colorectal cancer (CRC) and metastatic colon cancer (mCRC), sponsored by University Medical Center Utrecht. Primary endpoints: Dose-limiting toxicities and recommended phase II dose and Objective response rate. Started Jul 2020; status: completed.

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Drugs

binimetiniblapatinibvinorelbine
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Conditions

colorectal cancer (CRC)metastatic colon cancer (mCRC)

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