Trial intelligence / Profile preview

Relatlimab + nivolumab versus regorafenib or TAS-102 in later-line metastatic colorectal cancer

NL-OMON60754Phase 3Completed

Sponsor
Bristol Myers Squibb
Start
Dec 2022
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, open-label trial of relatlimab, nivolumab, regorafenib and trifluridine + tipiracil in colorectal cancer (CRC) and metastatic colorectal adenocarcinoma (mCRC) (2 arms), sponsored by Bristol Myers Squibb. Primary endpoints: Overall survival in randomized participants with PD-L1 CPS >= 1 and Overall survival in all randomized participants. Started Dec 2022; status: completed.

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Drugs

relatlimabnivolumabregorafenibtrifluridine + tipiracil
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Conditions

colorectal cancer (CRC)metastatic colorectal adenocarcinoma (mCRC)

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