Trial intelligence / Profile preview

Phase I study of [177Lu]Lu-NNS309 in advanced solid tumors

NL-OMON60811Phase 1Recruiting

Sponsor
Novartis
Start
May 2026
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta-minus Emitters → Radiopharmaceuticals, Gamma Emitters → Radiopharmaceuticals
Countries
1
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Overview

Phase 1, open-label trial of [177Lu]Lu-NNS309 in colorectal cancer (CRC), breast cancer, non-small cell lung cancer (NSCLC) and 1 more (4 cohorts), sponsored by Novartis. Primary endpoints: Safety and Tolerability. Started May 2026; status: recruiting.

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Drugs

[177Lu]Lu-NNS309
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Conditions

colorectal cancer (CRC)breast cancernon-small cell lung cancer (NSCLC)pancreatic adenocarcinoma (PDAC)

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