Trial intelligence / Profile preview

mRNA-3927 in genetically confirmed propionic acidemia

NL-OMON60874Phase 2Active, not recruiting

Sponsor
Moderna Inc
Start
May 2025
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Countries
1
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Overview

Phase 2, open-label trial of mRNA-3927 in propionic acidemia (PA) (3 arms), sponsored by Moderna Inc. Primary endpoints: Safety and tolerability and Metabolic decompensation event frequency. Started May 2025; status: active, not recruiting.

02

Drugs

mRNA-3927
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Conditions

propionic acidemia (PA)

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