Trial intelligence / Profile preview

TRUTH study of dasatinib + quercetin for fibrotic NAFLD

NL-OMON60890Phase 2Completed

Sponsor
Amsterdam University Medical Center
Start
Oct 2024
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
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Overview

Phase 2, randomised, double-blind trial in metabolic dysfunction-associated steatotic liver disease (MASLD) and hepatic fibrosis comparing Dasatinib + quercetin with Placebo control (2 arms). Primary endpoint: Primary histologic fibrosis response. Started Oct 2024; status: completed.

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Drugs

dasatinibquercetin
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Conditions

metabolic dysfunction-associated steatotic liver disease (MASLD)hepatic fibrosis

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