Trial intelligence / Profile preview

Domvanalimab + zimberelimab + chemotherapy versus pembrolizumab + chemotherapy in untreated metastatic non-small cell lung cancer

NL-OMON60907Phase 3Completed

Sponsor
Gilead Sciences
Start
May 2023
Modality
Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised trial in non-small cell lung cancer (NSCLC) comparing Domvanalimab + zimberelimab + chemotherapy with Pembrolizumab + chemotherapy (2 arms). Primary endpoints: Overall survival in PD-L1-positive participants and Overall survival in all randomized participants. Started May 2023; status: completed.

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Drugs

domvanalimabzimberelimabpembrolizumab
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Conditions

non-small cell lung cancer (NSCLC)

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