Trial intelligence / Profile preview

Phase 1/2 study of GSK5460025 monotherapy in dMMR/MSI-H solid tumors

NL-OMON61049Phase 2Recruiting

Sponsor
GSK
Start
Sep 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of GSK5460025 in Nonhematologic neoplasms, colorectal cancer (CRC) and endometrial cancer (EC) (3 arms), sponsored by GSK. Primary endpoints: Dose-limiting toxicities, Treatment-emergent serious adverse events and adverse events and 4 more. Started Sep 2026; status: recruiting.

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Drugs

GSK5460025
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Conditions

Nonhematologic neoplasmscolorectal cancer (CRC)endometrial cancer (EC)

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