Trial intelligence / Profile preview

Phase III study of NIO752 in progressive supranuclear palsy with open-label extension

NL-OMON61059Phase 3Not yet recruiting

Sponsor
Novartis
Start
Jun 2026
Modality
Vaccine mRNA → mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics
Countries
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Overview

Phase 3, randomised, double-blind trial of NIO752 in progressive supranuclear palsy (PSP), sponsored by Novartis. Primary endpoint: Change from baseline in rPSPRS-10 score at Week 72. Planned start Jun 2026; status: not yet recruiting.

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Drugs

NIO752
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Conditions

progressive supranuclear palsy (PSP)

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