Trial intelligence / Profile preview

FORAGER-2: vepugratinib versus placebo with enfortumab vedotin and pembrolizumab in FGFR3-altered advanced urothelial cancer

NL-OMON61066Phase 3Not yet recruiting

Sponsor
Eli Lilly and Company
Start
Mar 2026
Modality
Small Molecules
Countries
1
01

Overview

Phase 3, randomised, double-blind trial in transitional cell carcinoma (TCC) and bladder cancer comparing Vepugratinib + enfortumab vedotin + pembrolizumab with Placebo + enfortumab vedotin + pembrolizumab (2 arms). Primary endpoints: Safety and tolerability of vepugratinib in combination with enfortumab vedotin and pembrolizumab, Overall response rate and 1 more. Planned start Mar 2026; status: not yet recruiting.

02

Drugs

vepugratinib
03

Conditions

transitional cell carcinoma (TCC)bladder cancer

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