Trial intelligence / Profile preview

MERCURE methotrexate study in recurrent differentiated vulvar intraepithelial neoplasia

NL-OMON61076Phase 4Recruiting

Sponsor
Amsterdam University Medical Center
Start
Aug 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 4, open-label, single-arm trial of methotrexate in differentiated vulvar intraepithelial neoplasia (dVIN) and Kraurosis vulvae, sponsored by Amsterdam University Medical Center. Primary endpoints: Time to recurrence of differentiated vulvar intraepithelial neoplasia and Clinical response status. Started Aug 2026; status: recruiting.

02

Drugs

methotrexate
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Conditions

differentiated vulvar intraepithelial neoplasia (dVIN)Kraurosis vulvae

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