Trial intelligence / Profile preview

Asciminib in pediatric and young adults with relapsed or refractory Ph+ or ABL-class Ph-like ALL

NL-OMON61087Phase 2Not yet recruiting

Sponsor
Novartis
Start
Oct 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Allosteric Modulators → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
01

Overview

Phase 2, open-label trial of asciminib in acute lymphoblastic leukemia (ALL) (2 arms), sponsored by Novartis. Primary endpoints: Incidence of dose-limiting toxicities during cycle 1, Incidence and severity of adverse events and laboratory safety findings during cycle 1 and 1 more. Planned start Oct 2026; status: not yet recruiting.

02

Drugs

asciminib
03

Conditions

acute lymphoblastic leukemia (ALL)

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