Trial intelligence / Profile preview

MK-1045 versus blinatumomab in relapsed or refractory Philadelphia-negative CD19-positive B-cell acute lymphoblastic leukemia

NL-OMON61240Phase 3Not yet recruiting

Sponsor
Merck & Co.
Start
Jun 2026
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
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Overview

Phase 3, randomised, open-label trial of CN201 in B cell acute lymphoblastic leukemia (B-ALL), sponsored by Merck & Co. Primary endpoints: Complete remission within the first 3 treatment cycles, Number of participants with an adverse event and 3 more. Planned start Jun 2026; status: not yet recruiting.

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Drugs

CN201
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Conditions

B cell acute lymphoblastic leukemia (B-ALL)

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