Trial intelligence / Profile preview

VS-7375 in advanced KRAS G12D-mutant solid tumors

NL-OMON61243Phase 2Completed

Sponsor
Verastem Oncology
Start
Jun 2026
Modality
Small Molecules
Countries
1
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Overview

Phase 2, open-label trial of GFH375 in Nonhematologic neoplasms, pancreatic adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC) and 1 more (11 arms), sponsored by Verastem Oncology. Primary endpoints: Safety and tolerability, Dose-limiting toxicities in Part A/C and 2 more. Started Jun 2026; status: completed.

02

Drugs

GFH375
03

Conditions

Nonhematologic neoplasmspancreatic adenocarcinoma (PDAC)non-small cell lung cancer (NSCLC)colorectal adenocarcinoma

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