Trial intelligence / Profile preview

MK-1084 plus durvalumab versus placebo plus durvalumab after concurrent chemoradiotherapy in KRAS G12C-mutated unresectable stage II-III non-small cell lung cancer

NL-OMON61245Phase 3Not yet recruiting

Sponsor
Merck & Co.
Start
Jun 2026
Modality
PD-1/PD-L1 Inhibitors → Immune Checkpoint Inhibitors → Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in non-small cell lung cancer (NSCLC) comparing MK-1084 plus durvalumab with Placebo plus durvalumab (2 arms). Primary endpoint: Progression-Free Survival. Planned start Jun 2026; status: not yet recruiting.

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Drugs

calderasibdurvalumab
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Conditions

non-small cell lung cancer (NSCLC)

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