Trial intelligence / Profile preview

Perioperative capecitabine dose-finding within a DOC regimen for gastroesophageal adenocarcinoma

NL-OMON61395Phase 1Not yet recruiting

Sponsor
Erasmus MC
Start
Jul 2026
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of capecitabine in esophageal adenocarcinoma (EAC), gastroesophageal junction adenocarcinoma and gastric adenocarcinoma, sponsored by Erasmus MC. Primary endpoint: Maximum tolerated dose of perioperative capecitabine within DOC. Planned start Jul 2026; status: not yet recruiting.

02

Drugs

capecitabine
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Conditions

esophageal adenocarcinoma (EAC)gastroesophageal junction adenocarcinomagastric adenocarcinoma

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