Trial intelligence / Profile preview

Phase 2 study of rinatabart sesutecan monotherapy in advanced gastrointestinal cancers

NL-OMON61528Phase 2Not yet recruiting

Sponsor
Genmab
Start
Sep 2026
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 2, open-label, single-arm trial of rinatabart sesutecan in colorectal cancer (CRC), gastric cancer (GC), gastroesophageal junction adenocarcinoma and 4 more, sponsored by Genmab. Primary endpoint: Confirmed objective response rate. Planned start Sep 2026; status: not yet recruiting.

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Drugs

rinatabart sesutecan
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Conditions

colorectal cancer (CRC)gastric cancer (GC)gastroesophageal junction adenocarcinomaesophageal adenocarcinoma (EAC)pancreatic adenocarcinoma (PDAC)

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