Trial intelligence / Profile preview

Mucosal immunity during pollen allergen immunotherapy

NL-OMON61614Not yet recruiting

Sponsor
Rijnstate
Start
Jan 2027
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Countries
1
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Overview

Open-label trial of phleum pratense allergen extract, travoprost and Olea europaea allergen extract in allergic rhinitis (AR), allergic rhinoconjunctivitis (ARC) and allergic asthma (3 arms), sponsored by Rijnstate. Primary endpoint: Longitudinal within-patient changes in nasal mucosal inflammatory biomarkers. Planned start Jan 2027; status: not yet recruiting.

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Drugs

phleum pratense allergen extracttravoprostOlea europaea allergen extract
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Conditions

allergic rhinitis (AR)allergic rhinoconjunctivitis (ARC)allergic asthma

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