Trial intelligence / Profile preview

Ivonescimab plus chemotherapy with or without upfront stereotactic radiotherapy for NSCLC brain metastases

NL-OMON61741Phase 2Not yet recruiting

Sponsor
European Organisation for Research and Treatment of Cancer
Start
Dec 2026
Modality
Small Molecules, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 2, randomised, open-label trial of ivonescimab and pemetrexed in non-small cell lung cancer (NSCLC) (2 arms), sponsored by European Organisation for Research and Treatment of Cancer. Primary endpoint: Intracranial progression-free survival. Planned start Dec 2026; status: not yet recruiting.

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Drugs

ivonescimabpemetrexed
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Conditions

non-small cell lung cancer (NSCLC)

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