Trial intelligence / Profile preview

Phase 3 study of doravirine + islatravir versus bictegravir/emtricitabine/tenofovir alafenamide in treatment-naive adults with HIV-1

PACTR202403575006415Phase 3Recruiting

Sponsor
MSD
Start
Mar 2023
Modality
Small Molecules
Countries
2
01

Overview

Phase 3, randomised, double-blind trial in Human immunodeficiency virus infection type 1 comparing Doravirine + islatravir with Bictegravir + emtricitabine + tenofovir alafenamide (2 arms). Primary endpoints: Percentage of participants with HIV-1 RNA <50 copies/mL and Percentage of participants who experience adverse events and percentage of participants who discontinue study intervention due to adverse events. Started Mar 2023; status: recruiting.

02

Drugs

doravirineislatravirbictegraviremtricitabinetenofovir alafenamide
03

Conditions

Human immunodeficiency virus infection type 1

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