Trial intelligence / Profile preview

TOKOMEZA - Ebola Disease Therapeutics Trial

PACTR202502676012681Phase 3Not yet recruiting

Sponsor
Ministry of Health of Uganda
Start
Feb 2025
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
1
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Overview

Phase 3, randomised, open-label trial in Ebola virus disease (EVD) comparing Remdesivir, MBP134 and Remdesivir + MBP134 (3 arms). Primary endpoint: All-cause mortality at 28 days following randomisation. Planned start Feb 2025; status: not yet recruiting.

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Drugs

remdesivirMBP134
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Conditions

Ebola virus disease (EVD)

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