Trial intelligence / Profile preview

AES-trial in Niger for shortened multidrug-resistant tuberculosis treatment

PACTR202505593072442Not yet recruiting

Sponsor
Damian Foundation Niger
Start
Apr 2025
Modality
Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Randomised, open-label trial of bedaquiline, pretomanid, linezolid, moxifloxacin and levofloxacin in Tuberculosis (TB) (2 arms), sponsored by Damian Foundation Niger. Primary endpoint: Safety comparison between modified 5-month regimen and BPaLM. Planned start Apr 2025; status: not yet recruiting.

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Drugs

bedaquilinepretomanidlinezolidmoxifloxacinlevofloxacin
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Conditions

Tuberculosis (TB)

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