Trial intelligence / Profile preview

MK-8527 for HIV-1 pre-exposure prophylaxis

PACTR202509563273736Phase 3Not yet recruiting

Sponsor
MSD
Start
Sep 2025
Modality
Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in human immunodeficiency virus infection (HIV) comparing MK-8527 arm with FTC/TDF arm (2 arms). Primary endpoints: Adjudicated HIV-1 infection, Adverse events and 1 more. Planned start Sep 2025; status: not yet recruiting.

02

Drugs

mk-8527emtricitabine + tenofovir disoproxil
03

Conditions

human immunodeficiency virus infection (HIV)

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