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Gut health and immune responses to oral Rotarix vaccine in adults in Zambia
PACTR202605883953305Recruiting
- Sponsor
- Gates Foundation
- Start
- Mar 2026
- Modality
- Vaccines & Immunotherapeutics
- Countries
- 1
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Overview
Open-label, single-arm trial of human rotavirus RIX4414 strain vaccine in rotaviral diarrhea, sponsored by Gates Foundation. Primary endpoints: Feasibility of generating high-quality spatial transcriptomic data from intestinal biopsies and Participant completion of scheduled study procedures. Started Mar 2026; status: recruiting.
02
Drugs
human rotavirus RIX4414 strain vaccine
03
Conditions
rotaviral diarrhea
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