Trial intelligence / Profile preview

Phase 1b Ugandan pediatric study of R21 + RH5.1 + R78C with Matrix-M given with routine EPI vaccines

PACTR202610764919854Phase 1Not yet recruiting

Sponsor
University of Oxford
Start
Oct 2026
Modality
Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics, Recombinant Proteins and Enzymes
Countries
1
01

Overview

Phase 1, randomised, open-label trial of R21/Matrix-M, RH5.1, R78C and Matrix M in malaria (8 arms), sponsored by University of Oxford. Primary endpoints: Occurrence of solicited local and systemic adverse events, Occurrence of unsolicited adverse events and 1 more. Planned start Oct 2026; status: not yet recruiting.

02

Drugs

R21/Matrix-MRH5.1R78CMatrix M
03

Conditions

malaria

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