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Pentoxifylline and tocopherol prophylaxis before tooth extraction in cancer patients receiving bone-modifying agents
RBR-52ynn6jPhase 2Completed
- Sponsor
- IMIP
- Start
- Apr 2021
- Modality
- Small Molecules, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 2, open-label, single-arm trial of pentoxifylline and tocopherol in medication-related osteonecrosis of the jaw (MRONJ), sponsored by IMIP. Primary endpoint: Occurrence of osteonecrosis of the jaws after dental extraction. Started Apr 2021; status: completed.
02
Drugs
pentoxifyllinetocopherol
03
Conditions
medication-related osteonecrosis of the jaw (MRONJ)
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