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Topical metformin for melasma
RBR-6c7styjPhase 2
Key facts
- Status
- Completed
- Start
- May 2025
- Countries
- 1
- Sponsor
- Universidade Estadual de Ponta Grossa
- Modality
- Small Molecules
- Drugs
- metformin
- Conditions
- melasma
01
Overview
Phase 2, randomised, double-blind trial in melasma comparing Topical metformin with Placebo topical formulation (2 arms). Started May 2025; status: completed.
02
Design
2 arms- Study design
- RandomizedDouble-blind
Topical metformin
Participants receive topical metformin once daily for 8 weeks.
Placebo topical formulation
Participants receive matching placebo topical formulation once daily for 8 weeks.
03
Who it enrols
Adult women with facial melasma who use SPF 50 sunscreen are eligible. The study population described in the protocol consists of women with facial melasma, with planned enrollment of 40 participants.
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