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Long-Term Colchicine Steady-State Levels in Chronic Kidney Disease: Pharmacokinetic Profile and Potential Toxicity Risk (Hemodialysis Subtopic)

TCTR20250921005Not yet recruiting

Sponsor
Faculty of Medicine, Naresuan University
Start
Nov 2025
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules, Nucleic Acid-Directed Small Molecules → Small Molecules
Countries
1
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Overview

Open-label, single-arm trial of colchicine in chronic kidney disease (CKD) and end-stage kidney disease (ESKD), sponsored by Faculty of Medicine, Naresuan University. Primary endpoints: Steady-state colchicine pharmacokinetic parameters and Colchicine-related toxicity risk. Planned start Nov 2025; status: not yet recruiting.

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Drugs

colchicine
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Conditions

chronic kidney disease (CKD)end-stage kidney disease (ESKD)

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