Drug intelligence / Profile preview

18F-CDKi

Development stage: Unknown
Lead developer: Xiang'an Hospital of Xiamen University
Modality: Alpha Emitters → Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta Emitters → Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
Administration: Intravenous

Overview

18F-CDKi is a radiolabeled small molecule positron emission tomography (PET) imaging tracer designed to target cyclin-dependent kinases 4 and 6 (CDK4/6). Developed by researchers at Xiang'an Hospital of Xiamen University, this tracer is used to visualize and quantify the expression of CDK4/6 in tumors, particularly in patients with hormone receptor-positive (HR+), HER2-negative breast cancer. By measuring the molecular function of CDK4/6, 18F-CDKi PET imaging serves as a diagnostic tool to evaluate and predict the response to neoadjuvant therapies that combine aromatase inhibitors with therapeutic CDK4/6 inhibitors. This approach facilitates personalized treatment monitoring and the early detection of therapeutic resistance.

Other names: 18F-labeled CDK4/6 inhibitor[18F]CDKi

Targets

CDK4 (Cyclin-dependent kinase 4)CDK6 (Cyclin-dependent kinase 6)

Beyond the preview

Go deeper on 18F-CDKi.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on 18F-CDKi.

Explore the full profile