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4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide

Development stage: Unknown
Modality: Small Molecules

Overview

4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide is a small molecule compound with the molecular formula C17H20N4O2S and a molecular weight of 344.431. It belongs to the class of benzenesulfonamides, which are organic compounds containing a sulfonamide group attached to a benzene ring[6][1]. The compound has been identified as an experimental drug candidate but is not approved for any indication. It has shown activity against tyrosine-protein kinase JAK2, with reported IC50 values in the nanomolar range (e.g., IC50 = 78 nM), suggesting potential as an inhibitor of this kinase[6]. No primary indication or developer information is publicly available.

Other names: 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide

Targets

JAK2 (Janus kinase 2)

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