Drug intelligence / Profile preview

ADCOLD

Development stage
Unknown
Lead developer
Adwin Life Care
Modality
Small Molecules
Administration
Oral
01

Overview

ADCOLD is a fixed-dose combination medication manufactured and marketed by Adwin Life Care, primarily indicated for the symptomatic relief of the common cold, influenza, and allergic rhinitis. It typically contains a combination of three active pharmaceutical ingredients: paracetamol (acetaminophen), phenylephrine hydrochloride, and chlorpheniramine maleate. Paracetamol acts as an analgesic and antipyretic by inhibiting prostaglandin synthesis in the central nervous system. Phenylephrine is a sympathomimetic agent that serves as a nasal decongestant by specifically targeting alpha-1 adrenergic receptors to induce vasoconstriction in the nasal mucosa. Chlorpheniramine maleate is a first-generation alkylamine antihistamine that provides relief from sneezing, watery eyes, and runny nose by competing with histamine for H1-receptor sites on effector cells. The product is positioned as a finished commercial pharmaceutical rather than an investigational candidate.

Brand names
ADCOLD
02

Targets

ADRA1A (α1A)HRH1 (Histamine H1 Receptor)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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