Drug intelligence / Profile preview

Amorest 28

Development stage
Unknown
Lead developer
Campus Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Amorest 28 is a combined oral contraceptive (COC) marketed by CampusPharma for the prevention of pregnancy in women. It is a fixed-dose combination product containing the progestin norgestimate and the synthetic estrogen ethinylestradiol. As a third-generation contraceptive, it works primarily by suppressing the production of gonadotropins—follicle-stimulating hormone (FSH) and luteinizing hormone (LH)—to inhibit ovulation. Additionally, it induces changes in the cervical mucus to impede sperm penetration and alters the endometrium to discourage implantation. Norgestimate is notably associated with a lower risk of venous thromboembolism (VTE) compared to some other progestogens. The product is typically administered in a 28-day cycle consisting of 21 active hormone tablets and 7 inactive placebo tablets.

Brand names
Amorest 28Amorest28Amorest-28
02

Targets

ER (Estrogen receptor)PR (Progesterone receptor)

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