Drug intelligence / Profile preview

ampicillin-sulbactam + fluconazole

Development stage
Unknown
Lead developer
Pfizer
Modality
Small Molecules
Administration
Intravenous, Intramuscular, Oral
01

Overview

A combination of ampicillin-sulbactam, an antibiotic consisting of ampicillin (a penicillin-class antibiotic) and sulbactam (a beta-lactamase inhibitor), with fluconazole, a triazole antifungal medication. This combination may be used in treating mixed bacterial and fungal infections, though there are concerns about potential antagonistic interactions between these medications.

Brand names
Unasyn + Diflucan
02

Targets

β-lactamasePBP (Penicillin-binding protein family)CYP51A1 (Sterol 14α-demethylase)

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