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aztreonam + flucloxacillin
- Development stage
- Unknown
- Lead developer
- Bristol Myers Squibb
- Modality
- Small Molecules
- Administration
- Intravenous, Intramuscular
01
Overview
A double beta-lactam antibiotic combination consisting of aztreonam, a monobactam beta-lactam with pure anti-Gram-negative activity, and flucloxacillin, a penicillinase-resistant penicillin effective against Gram-positive bacteria. This combination provides broad-spectrum coverage for empirical treatment of serious infections, particularly in elderly patients.
02
Targets
PBP (Penicillin-binding protein family)β-lactamase
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