Drug intelligence / Profile preview

benaGene

Development stage
Unknown
Lead developer
Terra Biological
Modality
Small Molecules
Administration
Oral
01

Overview

benaGene is an oral nutraceutical supplement developed by Terra Biological LLC, featuring a thermally-stabilized form of oxaloacetate known as Anhydrous Enol-Oxaloacetate (AEO). Formulated with Vitamin C (ascorbic acid) to ensure shelf stability, benaGene functions as a calorie restriction mimetic. It is designed to activate molecular pathways typically triggered by caloric restriction, such as the induction of Sirtuin 1 (SIRT1) and Adenosine monophosphate-activated protein kinase (AMPK), as well as the modulation of the NAD+/NADH ratio. Marketed primarily for its anti-aging properties, mitochondrial support, and cellular energy enhancement, the product is available over-the-counter and has undergone clinical evaluation for its impact on metabolic health and longevity-associated biomarkers.

Brand names
benaGene
Other names
oxaloacetateAnhydrous Enol-OxaloacetateAEO
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)

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