Drug intelligence / Profile preview

bezacitinib

Development stage
Phase 3
Lead developer
Hangzhou Bangshun Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Bezacitinib (OB756) is an orally bioavailable small molecule Janus kinase (JAK) inhibitor developed by Hangzhou Bangshun Pharmaceutical. It is currently in Phase 1 clinical development, specifically being evaluated for the treatment of type 1 diabetes mellitus. The drug is designed to modulate immune signaling pathways that contribute to the autoimmune destruction of pancreatic beta cells. Clinical trials in healthy participants have been initiated to characterize its safety, tolerability, pharmacokinetics, and pharmacodynamics, including relative bioavailability when administered as a tablet formulation.

Brand names
Bangruishun邦瑞顺
Other names
bezacitinib
02

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