Drug intelligence / Profile preview

cangfu ovulation decoction

Development stage
Unknown
Lead developer
Shuguang Hospital
Administration
Oral
01

Overview

Cangfu Ovulation Decoction is a Traditional Chinese Medicine (TCM) herbal formula primarily investigated for its efficacy in treating infertility associated with Polycystic Ovary Syndrome (PCOS) and obesity. Developed by researchers at Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, the decoction is based on traditional principles aimed at resolving phlegm-dampness and blood stasis, which are believed to impede ovulation. The formula is typically used to regulate reproductive hormones, improve insulin sensitivity, and promote follicular maturation. Clinical studies, including randomized controlled trials registered in the Chinese Clinical Trial Registry (ChiCTR), have evaluated its impact on ovulation rates and pregnancy outcomes in overweight women with ovulatory dysfunction.

Other names
Cangfu ovulatory decoction
02

Targets

JAK2 (Janus kinase 2)STAT3 (Signal Transducer and Activator of Transcription 3)FOXO4 (Forkhead box protein O4)Plakophilin 3/Excision Repair Cross-Complementation Group 1/Mitogen-Activated Protein Kinase (PKP3/ERCC1/MAPK) signaling moduleAKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)LCN2 (Lipocalin-2)TP53 (Cellular Tumor Antigen p53 R175H)HSP90AA1 (Heat shock protein HSP90-alpha)

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