Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Chunwangbosim-dan
- Development stage
- Unknown
- Lead developer
- Korea Institute of Oriental Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Chunwangbosim-dan (also known as Cheonwangbosim-dan or Tian Wang Bu Xin Dan) is a traditional East Asian herbal prescription composed of 15 medicinal herbs, including Rehmannia glutinosa, Coptis japonica, and Angelica gigas. It is widely used as an over-the-counter (OTC) medicine in South Korea and other East Asian countries to treat insomnia, anxiety, depression, and heart palpitations. In addition to its traditional uses, Chunwangbosim-dan is being investigated for its potential therapeutic benefits in mild cognitive impairment (MCI), post-COVID-19 fatigue, and chronic pruritus. Network pharmacology and molecular docking studies suggest that its active components, such as coptisine and isoacetoside, modulate inflammatory and immune signaling pathways by interacting with key mediators like AKT1, JAK2, and EGFR.
- Brand names
- PyeongonSoon Shim Hwan
- Other names
- Cheonwangbosim-danCWBSDPyeong-onSoon-shim-hwanSoonsimhwanTian Wang Bu Xin Dan
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)EGFR (Epidermal growth factor receptor)JAK2 (Janus kinase 2)MEK
Beyond the preview
Go deeper on Chunwangbosim-dan.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Chunwangbosim-dan.