Drug intelligence / Profile preview

ciprofloxacin + rifaximin

Development stage
Phase 2
Lead developer
Salix Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Ciprofloxacin + rifaximin is a combination antibiotic therapy primarily used for treating chronic active refractory pouchitis. Ciprofloxacin is a fluoroquinolone antibiotic that treats a wide variety of infections, while rifaximin is a poorly absorbed rifamycin derivative. This combination has shown effectiveness in cases where other treatments have failed, with studies demonstrating significant improvement in patients with chronic active refractory pouchitis when treated with rifaximin 1g twice daily plus ciprofloxacin 500mg twice daily for two weeks.

Other names
rifaximin + ciprofloxacinciprofloxacin + rifaximin
02

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