didecyldimethylammoniumchloride + prednicarbate

This is a topical combination drug consisting of didecyldimethylammonium chloride (a quaternary ammonium compound with broad-spectrum antimicrobial activity) and prednicarbate (a medium-potency topical corticosteroid). Didecyldimethylammonium chloride acts as a bactericidal and fungicidal agent, disrupting microbial cell membranes. Prednicarbate reduces inflammation by inhibiting cytokine production in skin cells. The combination has been studied for the treatment of impetiginized eczema—eczema complicated by secondary bacterial infection—where it aims to address both infection and inflammation[1][4][5]. Didecyldimethylammonium chloride is also known for its use as a disinfectant in non-pharmaceutical settings, but in this context serves as an adjunctive antimicrobial agent. Prednicarbate is valued for its anti-inflammatory effects with lower risk of skin atrophy compared to other corticosteroids[9].

Other names

didecyl-dimethyl-ammonium chloride + prednicarbateBardac-22 + prednicarbate